pathogenic mechanisms – Communicable Diseases Research

Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19

코로나19 중증도에 따라 항체 표적 SARS-CoV-2 에피토프 레퍼토리 달라

Article

Published on 2022-12-012022-09-11
Journal: Virulence
[Category] COVID19(2023년), SARS, 진단, 치료법,

Reliability of multi-site UK Biobank MRI brain phenotypes for the assessment of neuropsychiatric complications of SARS-CoV-2 infection: The COVID-CNS travelling heads study

Article

Published on 2022-09-292022-11-16
Journal: PLoS ONE
[Category] SARS, 유전자 메커니즘,

Comparing the Cytokine Storms of COVID-19 and Pandemic Influenza

COVID-19와 유행성 인플루엔자의 사이토카인 폭풍 비교

Article

Published on 2022-08-012022-09-11
Journal: Journal of interferon & cytokine research : the of
[Category] COVID19(2023년), SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alteration caused Characteristics coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytokine cytokine profile Cytokine storm Cytokine storms Cytokines death determine diagnostic disease driving emerging respiratory viruses Factor flu Health help homology immune immune mechanism immune signature immunopathological immunopathology Immunotherapy increasingly Infection infections Influenza influenza. less Manifestations morbidity Outbreaks over pandemic pathogenic mechanisms Perspective Protective respiratory infections respiratory virus respiratory viruses SARS-CoV-2 severe acute respiratory syndrome Coronavirus Severe infection severe respiratory infection similarities similarity storm target targets threat translational unique
[DOI] 10.1089/jir.2022.0029 PMC 바로가기 [Article Type] Article

Human Kidney Organoids and Tubuloids as Models of Complex Kidney Disease

Review article

Published on 2022-05-012022-10-05
Journal: The American journal of pathology
[Category] 비임상,

Plasma Biomarkers of Neuropathogenesis in Hospitalized Patients With COVID-19 and Those With Postacute Sequelae of SARS-CoV-2 Infection

입원한 COVID-19 환자 및 SARS-CoV-2 감염의 급성 후유증이 있는 환자의 신경병증 발생에 대한 혈장 바이오마커

Article

Published on 2022-03-072022-09-11
Journal: Neurology® neuroimmunology & neuroinflammation
[Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, 치료법,

[키워드] Acidic Activation addition Antigen antigenemia antigenic antigenic stimulation Anxiety assessments association biochemical evidence Blood calculated CNS cognitive concentrations coronavirus correlated COVID-19 COVID-19 disease detectable detection develop diagnosis of COVID-19 dysfunction Encephalopathy enrolled Evidence evidence of exhibited groups healthy control Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient Infection initial Injury latent infection life light chain manifestation Measures Mild neurologic neuronal Neuropathogenesis Neuropsychiatric nucleocapsid antigen occur Older PASC pathogenic mechanism pathogenic mechanisms Patient patients patients hospitalized plasma plasma biomarker PNP presenting Protein recruited required respiratory Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 N Simoa Study participants subjects Symptom Symptoms symptoms onset These data were measured with COVID-19
[DOI] 10.1212/NXI.0000000000001151 PMC 바로가기 [Article Type] Article

The cognitive and psychiatric subacute impairment in severe Covid-19

심한 covid-19의인지 및 정신과 아 급성 손상

Article

Published on 2022-03-032022-09-10
Journal: Scientific Reports
[Category] MERS, SARS, 바이오마커, 치료기술,

[키워드] accelerate addition Anxiety Biomarkers Central nervous system infections Characteristics chemokine chemokines cognitive Cognitive function Cognitive neuroscience Cohort Concentration cortical Dementia Depression described develop Diseases Diseases of the nervous system domain elevated executive Factor functions General population healthy hospital discharge impairment independent Infection less long term Manifestations memory neurodegenerative Neurodegenerative diseases Neuroimmunology Neurologic impairment neurological Neuropsychiatric Outpatient pathogenic mechanisms Patient patients who survived plasma Principal component principal component analysis pro-inflammatory Psychiatric recruited SARS-CoV-2 SARS-COV-2 infection selective severe COVID-19 patients Severe infection severe SARS-CoV-2 syndrome systemic inflammation Trigger Working memory
[DOI] 10.1038/s41598-022-07559-9 PMC 바로가기 [Article Type] Article

Does acute and persistent metabolic dysregulation in COVID-19 point to novel biomarkers and future therapeutic strategies?

COVID-19의 급성 및 지속적인 대사 조절 장애는 새로운 바이오마커와 미래 치료 전략을 가리키는가?

Editorial

Published on 2022-02-242022-09-11
Journal: The European Respiratory Journal
[Category] COVID19(2023년), MERS, SARS, 바이오마커,

[키워드] Biomarker changes in COVID-19 dysregulation future therapeutic metabolomics outcome pathogenic mechanism pathogenic mechanisms Patient predict targets
[DOI] 10.1183/13993003.02417-2021 PMC 바로가기 [Article Type] Editorial

SARS-CoV-2: The Monster Causes COVID-19

SARS-CoV-2: 괴물이 COVID-19를 유발합니다

Review

Published on 2022-02-082022-09-11
Journal: Frontiers in Cellular and Infection Microbiology
[Category] COVID19(2023년), MERS, SARS, 치료기술,

C5a and C5aR1 are key drivers of microvascular platelet aggregation in clinical entities spanning from aHUS to COVID-19

C5a 및 C5aR1은 aHUS에서 COVID-19에 이르는 임상 기관에서 미세혈관 혈소판 응집의 주요 동인입니다

Article

Published on 2022-01-082022-09-11
Journal: Blood advances
[Category] SARS, 유전자 메커니즘,

[키워드] Activation acute respiratory syndrome added aggregation Alternative pathway antithrombogenic Atypical Bacterial infection Bacterial infections binding blockade C5a C5aR1 C5b-9 caused CCX168 Cell chronic inflammatory diseases clinical entity clinical implications Comorbidities Comorbidity complement complement system coronavirus COVID-19 Critical demonstrated develop driver dysfunction dysregulation Effect endothelial endothelial cells Endothelial dysfunction Endothelium Ex vivo Exocytosis Genetic hemolytic uremic syndrome highlight human serum Hyperactivation Infection Inflammatory diseases Microvascular thrombosis normal human serum P-selectin pathogenic mechanisms Patient patients treated Platelet platelet adhesion prothrombotic RalA rare disease Registered selectin serum severe acute respiratory syndrome Coronavirus severe COVID-19 severely ill patients suffered thrombosis Thrombus thrombus formation translate Trial triggered uremic syndrome viral infections von Willebrand factor
[DOI] 10.1182/bloodadvances.2021005246 PMC 바로가기 [Article Type] Article

Longitudinal Metabolomics Reveals Ornithine Cycle Dysregulation Correlates With Inflammation and Coagulation in COVID-19 Severe Patients

Microbiology

Published on 2021-12-032022-10-31
Journal: Frontiers in Microbiology
[Category] COVID-19,

[키워드] amino acid metabolism amino acids analyzed association biochemical Biochemical parameters Blood change Coagulation correlated COVID-19 COVID-19 patient COVID-19 patients creating cycle cytokine Cytokines diagnostic dipeptides discharge Disease progression drug dysregulation FIVE global pandemic humans Inflammation longitudinal longitudinal change marker metabolic disorder metabolic factor metabolite metabolites metabolome metabolomic metabolomics Mild nine ornithine ornithine cycle pathogenic mechanisms pathogenicity peptides potential mechanism provided SARS-CoV-2 SARS-COV-2 infection serum severe disease Severe patient severe patients significantly significantly higher valuable resource
[DOI] 10.3389/fmicb.2021.723818 PMC 바로가기 [Article Type] Microbiology